Can I Take 40 mg of Tadalafil (Cialis) for ED?

Is 40 mg of Cialis safe?

It’s risky to increase your Cialis dose to 40 mg. Here’s why: The drug affects other parts of the body, which can cause unwanted side effects.

It changes more than your penis

While Cialis works for ED by affecting the PDE5 enzyme in the penis, it also effects other PDE enzymes in tissues and cells in other areas of the body. For example, PDE5 is found in tissues in the lungs, kidneys, liver, brain, and platelets.

Cialis also affects PDE11 which is found in tissues in the heart, pancreas, pituitary, skeletal muscles, testes, and corpus cavernosum.

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