What is medroxyprogesterone?
Medroxyprogesterone is a progestin (a form of progesterone), a female hormone that helps regulate ovulation (the release of an egg from an ovary) and menstrual periods.
Medroxyprogesterone is used to treat conditions such as absent or irregular menstrual periods, or abnormal uterine bleeding. Medroxyprogesterone is also used to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens.
Medroxyprogesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Before taking this medicine
Medroxyprogesterone can cause birth defects. Do not use if this medicine you are pregnant. Tell your doctor right away if you become pregnant during treatment.
You should not use this medicine if you are allergic to medroxyprogesterone, or if you have:
- abnormal vaginal bleeding that has not been diagnosed;
- a hormone-related cancer such as breast or uterine cancer;
- liver disease; or
- a history of stroke or blood clot.
To make sure medroxyprogesterone is safe for you, tell your doctor if you have:
- heart disease, congestive heart failure, recent stroke or heart attack
- high blood pressure;
- high cholesterol or triglycerides;
- low levels of calcium in your blood;
- severe pelvic pain;
- recent miscarriage or abortion;
- migraine headaches;
- a thyroid disorder;
- kidney disease,
- diabetes; or
How should I take medroxyprogesterone?
Take medroxyprogesterone exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Medroxyprogesterone is usually given for only a few days in a row each month. You may need to start taking the medication on a certain day of your menstrual cycle, depending on why you are taking medroxyprogesterone. Follow your doctor’s instructions.
Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using medroxyprogesterone.
This medicine can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are taking medroxyprogesterone.
Store at room temperature away from moisture and heat.
Medroxyprogesterone side effects
Get emergency medical help if you have any signs of an allergic reaction to medroxyprogesterone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- vaginal bleeding if you have already gone through menopause;
- a light-headed feeling, like you might pass out;
- a breast lump;
- symptoms of depression (sleep problems, dizziness, mood changes, headache);
- jaundice (yellowing of the skin or eyes);
- swelling in your hands, ankles, or feet;
- heart attack symptoms–chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- signs of a stroke–sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
- signs of a blood clot in the lung–chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
- signs of a blood clot in your leg–pain, swelling, warmth, or redness in one or both leg