Pramipexole is used alone or with other medications to treat Parkinson’s disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move (“on-off syndrome”).This medication is also used to treat a certain medical condition (restless legs syndrome – RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep.Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.
How to use pramipexole oral
Read the Patient Information Leaflet provided by your pharmacist before you start taking pramipexole and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food, as directed by your doctor. Taking this medication with food may reduce nausea. To decrease the risk of side effects (e.g., drowsiness, low blood pressure) when you first start taking pramipexole, your doctor will slowly increase your dosage until the best dose for you is reached. Take this medication as prescribed. Do not increase your dose or take it more often than directed.
Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.
If you stop taking this medication for several days, you may need to increase your dose slowly back to your previous dosage. Talk with your doctor about how to restart the medication. Do not stop taking this medication without your doctor’s approval. Although very unlikely, if you suddenly stop taking this drug, you may have withdrawal symptoms (such as fever, muscle stiffness, confusion). Tell your doctor or pharmacist right away if you have withdrawal. If you have Parkinson’s disease and are stopping regular treatment with this drug, your doctor may lower your dose slowly to prevent withdrawal reactions. Consult your doctor or pharmacist for more details.
The dosage is based on your medical condition and response to treatment.
Nausea, dizziness, drowsiness, lightheadedness, trouble sleeping, constipation, headache, or dry mouth may occur. If these effects persist or worsen, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: fainting, mental/mood changes (such as confusion, depression, hallucinations, memory problems), unusual strong urges (such as increased gambling, increased sexual urges), increased difficulty moving/walking, muscle cramps/spasm, unusual posture changes (such as the neck or body bending forward), restlessness, decreased sexual ability, increased shakiness (tremor)/stiffness, swelling of the ankles/feet.
Get medical help right away if you have any very serious side effects, including: chest pain, fever, unusually fast/slow/irregular heartbeat, muscle pain/weakness, unusual tiredness, signs of kidney problems (such as change in the amount of urine), vision changes.
Some people taking pramipexole have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some cases, sleep occurred without any feelings of drowsiness beforehand. This sleep effect may occur anytime during treatment with pramipexole even if you have used this medication for a long time. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your risk of this sleep effect is increased by using alcohol or other medications that can make you drowsy. See also Precautions section.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.